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ASH 2023 | AFM13 with cord blood-derived NK-cell therapy in patients with refractory CD30-positive lymphomas

Yago Nieto, MD, PhD, The University of Texas MD Anderson Cancer Center, Houston, TX, presents results from a Phase I/II trial (NCT04074746) evaluating the safety profile and efficacy of cord blood-derived cytokine-induced natural killer (NK) cells followed by systemic AFM13, a CD30/CD16A bispecific antibody, in patients with refractory CD30+ lymphomas who were refractory to brentuximab vedotin. This treatment regimen yielded excellent tolerability, with robust overall survival (OS) and event-free survival (EFS) rates. This interview took place at the 65th ASH Annual Meeting and Exposition, held in San Diego, CA.

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Disclosures

Research Funding: Affimed, Astra Zeneca, Secura Bio