Jan P. Nicolay, MD, Ruprecht Karls University of Heidelberg, Mannheim, Germany, gives an overview of key updates presented at the EORT CLTF 2021 meeting, highlighting data from the Prospective Cutaneous Lymphoma International Prognostic Indices (PROCLIPI) study, and the identification of novel relevant pathways in cutaneous T-cell lymphoma (CTCL) and cutaneous B-cell lymphoma (CBCL). This interview took place at the EORTC Cutaneous Lymphoma Group 20-21 meeting in Marseille.