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iwCLL 2023 | Combining CAR-T with T cell-engaging bispecific antibodies to enhance efficacy in CLL murine models

In this interview, Martina Seiffert, PhD, German Cancer Research Center, Heidelberg, Germany, comments on an investigation into a treatment approach in which CD19 CAR T-cells (CAR-T) are combined with bispecific antibody (bsAb) treatment to improve efficacy. The therapy approach has been investigated in murine models of chronic lymphocytic leukemia (CLL) and in ex vivo primary culture models of CLL lymph node samples. This interview was recorded at the biennial International Workshop on Chronic Lymphocytic Leukemia (iwCLL) 2023 meeting, held in Boston, MA.

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