In this video, Peter Vandenberghe, MD, UZ Leuven, Leuven, Belgium, discusses the role of bridging therapy in the CAR T-cell therapy process. Previously, bridging therapy was only considered for high-risk patients or those at late stages of disease. However, it is now understood that patients achieving a partial response (PR) or complete response (CR) through bridging therapy exhibit better CAR-T outcomes. Prof. Vandenberghe highlights the need to integrate bridging therapy into CAR-T treatment and investigate the best type to decrease disease burden as much as possible before CAR-T infusion. This interview took place at the EBMT-EHA 6th European CAR T-cell Meeting in Valencia, Spain.
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