Hamza Hashmi, MD, Medical University of South Carolina, Charleston, SC, presents real-world data on the safety and efficacy of teclistamab for patients with heavily pretreated relapsed/refractory (R/R) multiple myeloma (MM). With a median follow-up of 3.5 months, the best overall response rate (ORR) was 65%, although a low progression-free survival (PFS) indicates that remission was not durable. Adverse events (AEs) of cytokine release syndrome (CRS) were generally well-managed with tocilizumab, while neurotoxicity was treated with dexamethasone. This interview took place at the 65th ASH Annual Meeting and Exposition, held in San Diego, CA.
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