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ASH 2025 | RADAR trial: Isa-VRDc induction and Isa-VRD consolidation in newly diagnosed ultra-high-risk myeloma

Karthik Ramasamy, MBBS, MRCP, FRCPath, PhD, Oxford University Hospitals NHS Foundation Trust, Oxford, UK, discusses the initial results from a cohort of the UK Myeloma Research Alliance (UKMRA) RADAR trial (ISRCTN46841867), which is evaluating the efficacy of isatuximab, bortezomib, lenalidomide, dexamethasone, and cyclophosphamide (Isa-VRDc) induction and Isa-VRD consolidation in newly diagnosed transplant-eligible patients with double hit ultra-high risk myeloma. Dr Ramasamy highlights that the study demonstrated activity in this high-risk patient population. This interview took place at the 67th ASH Annual Meeting and Exposition, held in Orlando, FL.

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