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ASH 2022 | Phase II study of inotuzumab ozogamicin in MRD+ B-ALL

Elias Jabbour, MD, The University of Texas MD Anderson Cancer Center, Houston, TX, describes the results of a Phase II study assessing inotuzumab ozogamicin in patients with B-cell acute lymphoblastic leukemia (B-ALL) who are measurable residual disease (MRD)-positive. The study reported that lower doses of fractionated inotuzumab ozogamicin is a well-tolerated option for MRD+ patients, including those with prior exposure to blinatumomab. This interview took place at the 64th ASH Annual Meeting and Exposition congress in New Orleans, LA.

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Disclosures

Takeda: Other: Advisory Role, Research Funding; Genentech: Other: Advisory Role, Research Funding; Adaptive Biotechnologies: Other: Advisory Role, Research Funding; Spectrum: Research Funding; Pfizer: Other: Advisory Role, Research Funding; Bristol Myers Squibb: Other: Advisory Role, Research Funding; Amgen: Other: Advisory Role, Research Funding; AbbVie: Other: Advisory Role, Research Funding.