Torsten Haferlach, MD, of MLL Munich Leukemia Laboratory, Munich, Germany, speaks about the current and future areas to be researched in the treatment of acute lymphoblastic leukemia (ALL), and then goes on to discuss the difficulties that researcher’s are facing concerning clinical trial design. This video was recorded at the 2018 European School of Hematology (ESH) Clinical Updates on Acute Leukemias, held in Budapest, Hungary.