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ASH 2023 | UM171 improves outcomes of cord-blood transplants in high-risk leukemia

Filippo Milano, MD, PhD, Fred Hutchinson Cancer Research Center, Seattle, WA, outlines a study investigating UM171-expanded cord blood transplants (CBT) in patients with high and very high-risk leukemias. UM171 is a small molecule that expands hematopoietic stem and progenitor cell lines and, when administered with CBT, produces extremely promising results in this cohort, with the majority of patients exhibiting a prolonged disease-free period. Following this success, a randomized trial is being planned to assess this treatment in larger cohorts. This interview took place at the 65th ASH Annual Meeting and Exposition, held in San Diego, CA.

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Disclosures

Research Funding: ExCellThera Inc.