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MDS 2023 | SINTRA-REV update: early lenalidomide treatment in non-transfusion dependent del(5q) LR-MDS

Maria Diez Campelo, MD, PhD, University of Salamanca, University Hospital Salamanca, gives a brief update on SINTRA-REV (NCT01243476), a Phase III study evaluating early treatment with lenalidomide vs placebo in non-transfusion dependent patients with low-risk myelodysplastic syndromes (MDS) with deletion 5q. Overall the study showed that this treatment did not promote clonal evolution and was a tolerable approach in this patient population. This interview took place at the 17th International Congress on Myelodysplastic Syndromes 2023 (MDS 2023) held in Marseille, France.

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