Arnon Nagler, MD, MSc, Sheba Medical Center, Tel-Aviv, Israel, discusses the cytogenetic abnormalities seen in acute myeloid leukemia (AML), the development of a cytogenetic risk score and how this is important to allogeneic stem cell transplantation (ASCT). This interview was recorded via an online conference call with The Video Journal of Hematological Oncology (VJHemOnc).