Andrea Visentin, MD, PhD, University of Padua, Padova, Italy, discusses exciting updates on the BTK inhibitors acalabrutinib, zanubrutinib and ibrutinib, which will be presented at the virtual European Hematology Association (EHA) Congress 2021. In particular, Dr Visentin highlights updates on the ELEVATE CLL TN trial (NCT02475681), the ELEVATE CLL R/R trial (NCT02477696) and the ALPINE trial (NCT03734016).