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EHA 2023 | An overview of the safety profile of FLT3 inhibitors in AML

Michael Loschi, MD, PhD, University Hospital of Nice, Cote d’Azur University, Nice, France, comments on the safety profile of currently available and investigational FLT3 inhibitors for acute myeloid leukemia (AML) including sorafenib, midostaurin, gilteritinib, quizartinib, and crenolanib. Dr Loschi highlights the importance of cardiac monitoring and of being aware of potential interactions with cytochrome P450 3A4 (CYP3A4). This interview took place at the 28th Congress of the European Hematology Association (EHA) 2023 in Frankfurt, Germany.

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Honorarium : Novartis, Gilead, Pfizer, Sobi, BMS, Abbvie, Janssen, Astra zeneca, Alexion, GSK, Incyte, Morphosys, Telios, Kartos