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EBMT 2023 | Novel dual-targeting CD19/22 CAR-T therapy in relapsed ALL

Antonio Pérez-Martínez, MD, PhD, La Paz University Hospital, Madrid, Spain, shares insight into a novel dual-targeting CD19/22 CAR-T therapy for patients with acute lymphoblastic leukemia (ALL). Whilst CD19 CAR-T therapy has been revolutionary for the treatment of ALL, relapse can occur in up to 50% of patients. Dr Pérez-Martínez goes on to discuss the preliminary results from a small cohort of patients that underwent CD19/22 CAR-T infusion following relapse on CD19 CAR-T therapy. This interview took place at the 49th Annual Meeting of the European Group for Blood and Marrow Transplantation (EBMT) held in Paris, France.

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