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ASH 2022 | The benefit of allogeneic transplantation in patients with TP53-mutated AML

Mark Litzow, MD, Mayo Clinic, Rochester, MN, shares the results of a study that evaluated the outcomes of patients with TP53-mutated acute myeloid leukemia (AML) following allogeneic hematopoietic stem cell transplantation (alloHSCT). The study showed that patients in first remission who received a transplant had better outcomes than those who didn’t, therefore demonstrating that alloHSCT should be offered to eligible patients with TP53-mutated AML. This interview took place at the 64th ASH Annual Meeting and Exposition congress in New Orleans, LA.

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Disclosures

Amgen: Research Funding; Astellas: Research Funding; Novartis: Research Funding; Syndax: Research Funding; Jazz: Consultancy, Membership on an entity’s Board of Directors or advisory committees; Actinium: Research Funding; Pluristem: Research Funding; Biosight: Consultancy, Other: Data Monitoring Board; Abbvie: Research Funding.