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ASH 2023 | The risk of heart failure in MPNs and the rate of CV-related readmissions following heart failure

Orly Leiva, MD, NYU Langone Health, New York City, NY, highlights the increased risk of heart failure in patients with myeloproliferative neoplasms (MPNs) and comments on a study that indicated an increased likelihood of cardiovascular (CV) and thrombotic readmissions in patients with myelofibrosis (MF) who have been hospitalized for heart failure. In JAK2-mutant mice, adverse cardiac remodeling has been observed, suggesting that patients with MPNs who harbor this mutation are at higher risk of experiencing heart failure. This interview took place at the 65th ASH Annual Meeting and Exposition, held in San Diego, CA.

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