iwCLL 2023 | Time-limited venetoclax-rituximab in R/R CLL patients previously exposed to BTKi’s
In this video, Thomas Lew, MBBS(Hons), Peter MacCallum Cancer Centre and Royal Melbourne Hospital, Melbourne, Victoria, Australia, discusses a study which aimed to assess the efficacy of a time-limited venetoclax-rituximab regimen in patients with relapsed/refractory (R/R) chronic lymphocytic leukemia (CLL) previously exposed to covalent BTK inhibitors (BTKi’s). Although overall response rate and complete remission rate were high, with a median progression-free survival of 26 months, treatment-free remissions were rare, which means feasibility of time-limited therapies in this context is unclear. This interview was recorded at the biennial International Workshop on Chronic Lymphocytic Leukemia (iwCLL) 2023 meeting, held in Boston, MA.
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