Katharina Holstein, MD, University Medical Center Hamburg-Eppendorf, Hamburg, Germany, comments on unmet needs in hemophilia B, drawing focus on the challenges of treating patients who develop factor IX (FIX) inhibitors. Dr Holstein discusses the problems that can arise with immune tolerance induction (ITI) in these patients, and shares some recommended approaches and novel therapies which may improve patient outcomes. This interview took place at the 31st Congress of the International Society on Thrombosis and Haemostasis (ISTH), held in Montréal, Canada.
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