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ASH 2024 | Long-term follow-up of OPTIMUM/Muknine: stratified treatment for patients with high-risk myeloma

Martin Kaiser, MD, FRCP, FRCPath, The Royal Marsden NHS Foundation Trust, London, UK, comments on the long-term follow-up of the OPTIMUM/Muknine trial (NCT03188172), which explored stratified treatment approaches for patients with high-risk multiple myeloma. Results demonstrated that 61% of patients remained progression-free at five years, and Dr Kaiser further notes that consolidation therapy is crucial for maintaining intensity in high-risk disease. The trial’s findings suggest the need for comprehensive genetic and gene expression profiling to personalize care and tailor treatment approaches for individual patients. This interview took place at the 66th ASH Annual Meeting and Exposition, held in San Diego, CA.

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