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ASH 2015 | Overview of the Phase I study with acalabrutinib (ACP-196) in CLL

Jacqueline Barrientos, MD, from the North Shore-Long Island Jewish Health System in New York, discusses the drug acalabrutinib (ACP-196), a second generation Bruton’s tirosine kinase (BTK) inhibitor that demonstrates reduced off-target effects. Dr Barrientos provides an overview of the Phase I study, where 965 of patients responded to treatment, including patients that have been through partial remission with lymphocytosis.

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