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CAR-T Meeting 2023 | IL3-zetakine coupled to a CD33 costimulatory receptor as a dual-targeting CAR approach in AML

In this video, Vincenzo Perriello, MD, PhD, University of Perugia, Perugia, Italy, briefly discusses the challenges with implementing efficacious CAR-T products in the treatment of acute myeloid leukemia (AML), and further highlights a novel dual-targeting approach being explored using an anti-CD123 IL-3 zetakine coupled to a CD33 costimulatory receptor. This interview took place at the EBMT-EHA 5th European CAR T-cell Meeting held in Rotterdam, The Netherlands.

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