RAS mutations are the most common genetic aberrations observed in multiple myeloma (MM). In this video, Hanne Norseth, MD, Oslo University Hospital, Oslo, Norway, introduces the Phase I TG01 study (NCT05841550), which assesses the use of vaccination against mutated RAS in patients with myeloma. Patients enrolled in the trial have either high-risk smoldering myeloma (HR-SMM) or stable/indolent disease, meaning the effect of the vaccine can be studied. This interview took place at the 29th Congress of the European Hematology Association (EHA) in Madrid, Spain.
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