ASH 2023 | Lacutamab, an anti-KIR3DL2 monoclonal antibody, in the treatment of R/R PTCL
Swaminathan Iyer, MD, The University of Texas MD Anderson Cancer Center, Houston, TX, discusses a study (NCT05321147) investigating lacutamab, an anti-KIR3DL2 monoclonal antibody, in the treatment of relapsed/refractory (R/R) peripheral T-cell lymphoma (PTCL). This agent attracts NK cells to attack cancer cells, and models have shown a synergistic effect when combined with chemotherapy regimens such as CHOP or bendamustine. This interview took place at the 65th ASH Annual Meeting and Exposition, held in San Diego, CA.
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Disclosures
Consultancy: Salarius, Acrotech, CRISPR, Seagen, Yingli; Research Funding: Pfizer, Ono, Astra Zeneca, Legend, Acrotech, Innate, CRISPR, Seagen, Merck, Drenbio, Yingli; Speakers Bureau: CuraBio, American Society of Hematology, American Society of Transplant and Cellular Therapy.
