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ASH 2025 | Long-term responders from the Phase III DREAMM-7 study of Bela-Vd versus Dara-Vd in R/R myeloma

Vania Hungria, MD, PhD, Santa Casa Medical School and Clinica São Germano, São Paulo, Brazil, discusses the results of a post-hoc analysis of long-term responders from the Phase III DREAMM-7 study (NCT04246047), comparing belantamab mafodotin plus bortezomib and dexamethasone (Bela-Vd) to daratumumab plus bortezomib and dexamethasone (Dara-Vd) in patients with relapsed/refractory multiple myeloma (RRMM). The analysis demonstrated that long-term responders had deeper responses and higher rates of measurable residual disease (MRD) negativity with Bela-Vd, corresponding to higher progression-free survival (PFS) rates. This interview took place at the 67th ASH Annual Meeting and Exposition, held in Orlando, FL.

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