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ASH 2022 | Beat AML Master sub-study: enasidenib and response-driven addition of azacitidine in IDH2m AML

Eytan Stein, MD, Memorial Sloan Kettering Cancer Center, New York, NY, shares some results from a sub-study of the Beat-AML Master trial (NCT03013998), which is evaluating the safety and efficacy of enasidenib followed by response-driven addition of azacitidine for the treatment of patients with IDH2-mutated acute myeloid leukemia (AML). This interview took place at the 64th ASH Annual Meeting and Exposition congress held in New Orleans, LA.

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Disclosures

Astellas Pharmaceutical, Agios Pharmaceuticals, and Genentech: Consultancy, Membership on an entity’s Board of Directors or advisory committees; PTC Therapeutics and Syros: Membership on an entity’s Board of Directors or advisory committees; Syndax: Consultancy, Research Funding; Amgen, AbbVie, Seattle Genetics, and Biotheryx: Consultancy; Daiichi-Sankyo, Celgene Pharmaceuticals, and Novartis: Consultancy, Membership on an entity’s Board of Directors or advisory committees, Research Funding; Auron Therapeutics: Current equity holder in private company; PinotBio, Bristol Myers Squibb, Jazz Pharmaceuticals, Foghorn Therapeutics, Blueprint Medicines, Gilead Sciences, Janssen Pharmaceuticals: Consultancy; Bayer: Research Funding.