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SOHO 2022 | Current and future treatment strategies for blast-phase CML

In this video, Mhairi Copland, MB ChB, PhD, University of Glasgow, Glasgow, UK, discusses current and future treatment approaches for blast-phase chronic myeloid leukemia (BP-CML). Prof. Copland first highlights the importance of continuing to develop and improve treatment options for patients with BP-CML, and then goes on to share some findings from the MATCHPOINT trial (ISRCTN98986889), which evaluated the efficacy of ponatinib in combination with FLAG-IDA chemotherapy in patients with BP-CML. To conclude, Prof. Copland highlights other studies exploring combination approaches in BP-CML and the potential role of CAR-T therapy and antibodies. This interview took place at the Tenth Annual Meeting of the Society of Hematologic Oncology (SOHO) held in Houston, TX.

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M.C. has received research funding from Cyclacel and Incyte, is/has been an advisory board member for Novartis, Incyte, Jazz Pharmaceuticals, Pfizer and Servier, and has received honoraria from Astellas, Novartis, Incyte, Pfizer and Jazz Pharmaceuticals.