Florence Cymbalista, MD, Hôpital Avicenne, Bobigny, France, comments on the need to move towards time-limited treatment for patients with chronic lymphocytic leukemia (CLL) in the frontline setting, highlighting some of the toxicities associated with continuous treatment. Prof. Cymbalista additionally outlines some promising time-limited treatment strategies that are currently under investigation, including venetoclax-based combinations or time-limited treatment with a BTK inhibitor with re-treatment upon progression, and various MRD-guided clinical trials. This interview took place at the 2022 European Research Initiative on CLL (ERIC) Meeting.
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