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EHA 2023 | Long-term findings from MCL0208: lenalidomide maintenance post autoSCT in MCL

Marco Ladetto, MD, Hospital SS. Antonio e Biagio and Cesare Arrigo, Alessandria, Italy, discusses the long-term results of the Phase III MCL0208 trial (NCT02354313). The study evaluated lenalidomide maintenance therapy after autologous stem cell transplantation (autoSCT) for mantle cell lymphoma (MCL). The two-year lenalidomide therapy demonstrated an early benefit to progression-free survival (PFS) which was not maintained once lenalidomide was interrupted, thus emphasizing the importance of long-term maintenance therapy post autoSCT. This interview took place at the 28th Congress of the European Hematology Association (EHA) 2023 in Frankfurt, Germany.

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Disclosures

Consultancy, participation to advisory boards, invitation to scientific meetings, institutional research support and contracts with: AbbVie, Acerta, Amgen, ADC Therapeutics, BeiGene, Celgene/BMS, Eusapharma, GSKI, Gentili, Gilead/Kite, Lilly, Novartis, Incyte J&J, Jazz, Regeneron, Roche, Sandoz. Non-financial interests: PI or strategic investigator in studies supported by: Celgene, J&J, BeiGene, ADC Therapeutics