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ASH 2023 | Retrospective real-world study evaluating compassionate use of ponatinib in R/R Ph-like ALL

In this video, Sabina Chiaretti, MD, PhD, University of Rome, Rome, Italy, discusses the results of a retrospective real-world study evaluating the safety and efficacy of ponatinib for patients with relapsed/refractory (R/R) Philadelphia chromosome-like (Ph-like) acute lymphoblastic leukemia (ALL). Dr Chiaretti indicates that compassionate use of ponatinib resulted in a promising response rate and allowed patients to be bridged to allogeneic stem cell transplantation (alloSCT) or CAR T-cell therapy. This interview took place at the 65th ASH Annual Meeting and Exposition, held in San Diego, CA.

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Incyte: Membership on an entity’s Board of Directors or advisory committees; Abbvie: Membership on an entity’s Board of Directors or advisory committees; Gilead: Membership on an entity’s Board of Directors or advisory committees; Pfizer: Membership on an entity’s Board of Directors or advisory committees; Amgen: Membership on an entity’s Board of Directors or advisory committees.