Theo de Witte, MD, Radboud University Medical Center, Nijmegen, discusses the inception of stem cell transplantation for the treatment of myelodysplastic syndromes (MDS). Theo goes on to discuss the growth of transplantation in this landscape, and the method’s current status in the field. The Netherlands. This interview took place at the 2nd Regional Symposium on Myelodysplastic Syndromes (MDS 2020), held in Tel Aviv, Israel.