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EHA 2023 | Feasibility of second CART19 administration with rituximab-based lymphodepletion in R/R B-ALL

Valentín Ortiz-Maldonado, MD, Hospital Clinic de Barcelona, Barcelona, Spain, discusses the results of a study evaluating the feasibility of second CAR-T therapy administration in patients with B-cell acute lymphoblastic leukemia (B-ALL) with an adapted lymphodepletion regimen. The findings revealed that second CART19 infusion with prior rituximab-based lymphodepletion led to long-term remissions in a subset of patients. This interview took place at the 28th Congress of the European Hematology Association (EHA) 2023 in Frankfurt, Germany.

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