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ASH 2022 | Moving towards personalized therapy in CLL & sequencing BTK inhibitors

Jennifer Woyach, MD, Ohio State University College of Medicine, Columbus, OH, talks on personalizing therapy for patients with chronic lymphocytic leukemia (CLL), commenting on the optimal strategy to sequence BTK inhibitors. According to Dr Woyach, it is best to start with a covalent BTK inhibitor and then continue with a non-covalent BTK inhibitor. Additionally, Dr Woyach highlights the advent of non-covalent BTK inhibitors, which hold great promise both alone or in combination with other agents. This interview took place at the 64th ASH Annual Meeting and Exposition congress in New Orleans, LA.

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Disclosures

Karyopharm Therapeutics: Research Funding; Schrodinger: Research Funding; Newave: Consultancy; Genentech: Consultancy; Pharmacyclics: Consultancy; ArQule: Consultancy; MorphoSys: Consultancy, Research Funding; Loxo@Lilly: Research Funding; AbbVie: Consultancy, Research Funding; Janssen: Consultancy; BeiGene: Consultancy; AstraZeneca: Consultancy.