Paul Richardson, MD, Dana-Farber Cancer Institute, Boston, MA, comments on the efficacy of the combination of mezigdomide plus dexamethasone and bortezomib or carfilzomib in relapsed/refractory (R/R) multiple myeloma. Dr Richardson highlights that the combination of mezigdomide with bortezomib generated response rates in excess of 70-80% and further shares the rationale for the ongoing SUCCESSOR-1 and SUCCESSOR-2 trials (NCT05519085; NCT05552976). This interview took place at the 66th ASH Annual Meeting and Exposition, held in San Diego, CA.
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