Sarah Tasian, MD, The Children’s Hospital of Philadelphia, Philadelphia, PA, gives an overview of promising novel strategies for the treatment of patients with Philadelphia chromosome (Ph)-like acute lymphoblastic leukemia (ALL), including the use of tyrosine kinase inhibitors (TKIs) for patients with ABL-class alterations and ruxolitinib for patients with JAK pathway alterations. Dr Tasian also comments on the importance of understanding the disease biology of Ph-like ALL and translating these findings into clinical practice. This interview took place at the American Association for Cancer Research (AACR) Annual Meeting 2023 in Orlando, FL.
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