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ICML 2019 | Ibrutinib in DLBCL: revelations from further analysis of PHOENIX

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Wyndham Wilson

The Phase III PHOENIX trial (NCT01855750) enrolled non-germinal center B-cell-like DLBCL patients and treated them with ibrutinib in combination with R-CHOP; the results were dissapointing, but could there be more to this than meets the eye? Here, Wyndham Wilson, MD, PhD, Center for Cancer Research, National Cancer Institute, Bethesda, MD, discusses the analysis of the results according to age, which revealed a number of interesting facts. He also discusses the concordance between IHC and gene expression profiling for the subtyping of DLBCL. This interview took place at the 15th International Conference on Malignant Lymphoma (ICML), in Lugano, Switzerland.

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