Eleni Gavriilaki, MD, PhD, G Papanicolaou Hospital, Thessaloniki, Greece, discusses recent advances in strategies to optimize the outcomes of patients with acute myeloid leukemia (AML) who receive an allogeneic transplant, including reduced-intensity conditioning (RIC) and more personalized treatment approaches. This interview took place at the European Hematology Association (EHA) Congress 2022 held in Vienna, Austria.