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CAR-T Meeting 2024 | First-in-human tandem expanded-NK and BCMA-CAR-NK cell infusion

Antonio Carrasco-Yalán, MD, British American Clinic, San Isidro, Peru, discusses a new natural killer (NK)-cell product engineered from NK-cells and a second generation CAR using a lipid nanoparticle (LNP) technology platform that allows for efficient delivery of anti-BCMA mRNA into the expanded-NK cells. Dr Carrasco-Yalán comments on the curative potential of this first-in-human tandem expanded-NK and BCMA-CAR-NK cell infusion, highlighting the benefits of this approach in patients who are not eligible for or do not have access to CAR-T. This interview took place at the EBMT-EHA 6th European CAR T-cell Meeting in Valencia, Spain.

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Disclosures

Investigator: MSD; Speaker: MSN, varifarma; Advisor: Immunovacell.