Antonio Cuneo, MD, PhD, University of Ferrara, Ferrara, Italy, outlines the impact of the COVID-19 pandemic on the treatment of chronic lymphocytic leukemia (CLL) in Italy, and outlines the risk of COVID-19 high-risk disease in patients with CLL. Dr Cuneo also discusses the use of the BTK inhibitor ibrutunib, which may show efficacy against the COVID-19 pandemic. This interview was recorded via an online conference call with The Video Journal of Hematological Oncology (VJHemOnc).