Jorge Castillo, MD, Dana-Farber Cancer Institute, Boston, MA, talks on promising therapies that are being developed for the treatment of Waldenström’s macroglobulinemia (WM), including fixed-duration triplet regimens, BTK inhibitor combination strategies, CLR 131, loncastuximab tesirine, and CAR-T therapy. This interview took place at the European Hematology Association (EHA) Congress 2022 held in Vienna, Austria.