Prithviraj Bose, MD, The University of Texas MD Anderson Cancer Center, Houston, TX, comments on the potential impact of navtemadlin on the treatment landscape of myeloproliferative neoplasms (MPNs), noting that it is the first MDM2 inhibitor to proceed to an advanced stage of development in MPNs. The agent is currently being investigated in the Phase III POIESIS study (NCT06479135), which has a unique design outlined by Dr Bose. This interview took place at the 66th ASH Annual Meeting and Exposition, held in San Diego, CA.
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