Mariana Bastos, MD, PhD, Gregorio Marañón University General Hospital, Madrid, Spain, discusses advancements in targeted therapies for aggressive lymphoma. She highlights early-line treatments combining novel cereblon E3 ligase modulators (CELMoDs) or atezolizumab with the R-CHOP regimen. In the relapsed/refractory (R/R) setting, she notes the combinations of glofitamab with a novel CD19/4-1BB T-cell engager and epcoritamab with polatuzumab vedotin-R-CHP (pola-R-CHP). This interview took place at the 29th Congress of the European Hematology Association (EHA) in Madrid, Spain.
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