Brian Durie, MD, Cedars-Sinai Samuel Oschin Cancer Center, Los Angeles, CA, discusses a comparison of daratumumab, lenalidomide, and dexamethasone (D-Rd) to bortezomib, lenalidomide, and dexamethasone (VRd) using data from the SWOG S0777 (NCT00644228) and MAIA (NCT02252172) trials. The findings show that D-Rd can be administered for longer, while VRd often needs to be stopped due to the risk of neuropathy, making D-Rd a more suitable option, particularly for older and frail patients. This interview took place at The 10th World Congress on Controversies in Multiple Myeloma (COMy) in Paris, France.
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