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EHA 2022 | Humanized versus murinized CD19/CD22 CAR-T cell therapy for R/R B-cell lymphoma
In this video, Peihua Lu, MD, Beijing Lu Daopei Institute of Hematology, and Hebei Yanda Lu Daopei Hospital, Langfang, China, discusses the results of a study comparing the safety and efficacy of humanized versus murinized dual-targeting CD19/CD22 CAR-T cells for relapsed/refractory (R/R) lymphoma. While both products were well-tolerated, the overall response rate (ORR) was higher in patients receiving humanized CAR-T cells, and Dr Lu mentions the need for a longer follow-up of this study. This interview took place at the European Hematology Association (EHA) Congress 2022 held in Vienna, Austria.
