David Maloney, MD, PhD, Fred Hutchinson Cancer Center, Seattle, and Johannes Schetelig, MD, WA, University of Dresden, Dresden, Germany, speaking at a roundtable discussion at the 18th International Workshop on Chronic Lymphocytic Leukemia (iwCLL) Biennial Meeting, held in Edinburgh, UK. The speakers elaborate on the future of CAR-T and cellular therapy in chronic lymphocytic leukemia (CLL), particularly as an alternative to allogeneic stem cell transplantation.