Kerry Rogers, MD, The Ohio State University, Columbus, OH, outlines the results of a three-year follow up of the Phase II trial (NCT02427451) of obinutuzumab in combination with ibrutinib and venetoclax in patients with relapsed/refractory or previously untreated chronic lymphocytic leukemia (CLL). The follow-up study found that fixed duration of obinutuzumab plus ibrutinib plus venetoclax resulted in high overall response rates and undetectable minimal residual disease status, with remissions remaining durable at 36 months. This interview took place during the 62nd American Society of Hematology (ASH) Annual Meeting and Exposition, 2020.