Giampaolo Merlini, MD, Foundation IRCCS Policlinico San Matteo, University of Pavia, Pavia, Italy, talks on AL amyloidosis management during the pandemic, specifically highlighting the fragility of this patient population and how telemedicine can avoid unnecessary contact. Prof. Merlini goes on to discuss the difficulties being faced in terms of trial conduction due to COVID-19. This interview was recorded via an online conference call with The Video Journal of Hematological Oncology (VJHemOnc).