Umberto Vitolo, MD, Candiolo Cancer Institute, FPO-IRCCS, Turin, Italy, discusses standard of care treatment approaches in mantle cell lymphoma (MCL) and further comments on the potential role of chemotherapy-free regimens. Prof. Vitolo first highlights treatment approaches for younger and elderly patients, and then goes on to discuss the efficacy of combining rituximab with ibrutinib and venetoclax. To conclude, Prof. Vitolo comments on the need to improve treatment options for patients with high-risk disease, highlighting the promise of using CAR-T cell therapy in earlier lines of treatment, and clinical trials in this space. This interview took place at the Tenth Annual Meeting of the Society of Hematologic Oncology (SOHO) held in Houston, TX.
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