Hege Garelius, MD, Sahlgrenska University Hospital, Göteborg, Sweden, outlines unmet needs in myelodysplastic syndromes (MDS), which include the treatment of patients who relapse following allogeneic hematopoietic stem cell transplantation (alloHSCT), and the management of patients with TP53 mutations. This interview took place at the European Hematology Association (EHA) Congress 2022 held in Vienna, Austria.