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ASH 2023 | ASCEMBL: asciminib versus bosutinib in third-line treatment of CP-CML

Michael Mauro, MD, Memorial Sloan Kettering Cancer Center, New York, NY, discusses the Phase III ASCEMBL trial (NCT03106779), comparing the safety and efficacy of asciminib versus bosutinib for the treatment of patients with chronic phase chronic myeloid leukemia (CP-CML) who have received two or more previous lines of therapy. After a median follow-up of four years, the safety and efficacy of asciminib were superior, with evidence of greater therapeutic benefit when it is used earlier in treatment. This interview took place at the 65th ASH Annual Meeting and Exposition, held in San Diego, CA.

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Disclosures

Memorial Sloan Kettering Cancer Center: Institutional Research Funding; Novartis: Consulting/Advisory Honorarium.