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IMS 2024 | The future of CAR-T and bispecifics in myeloma: successful integration into earlier lines

Borja Puertas, MD, University Hospital of Salamanca, Salamanca, Spain, discusses the future of CAR T-cell therapy and bispecific antibodies for treating multiple myeloma (MM), emphasizing the necessity to incorporate them into earlier treatment lines due to an increasing number of patients becoming triple-class exposed or refractory after minimal prior treatment. Dr Puertas highlights CAR T-cell therapy as a potential standard of care for high-risk patients, with emerging evidence supporting its use as first-line consolidation therapy for patients with suboptimal responses. Similarly, bispecifics may prove effective at first relapse in those with aggressive disease or as maintenance/consolidation in early lines. This interview took place at the 21st International Myeloma Society (IMS) Annual Meeting, held in Rio de Janeiro, Brazil.

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